|
KMID : 1035320150420010015
|
|
Korean Society for Dental Materials
2015 Volume.42 No. 1 p.15 ~ p.20
|
|
|
Effects of non-thermal atmospheric pressure air plasma on gene expression at SLAtreated titanium surfaces
|
|
Seo Hye-Yeon
Kang Min-Kyung
Choi Yu-Ri
Kwon Jae-Sung
Choi Eun-Ha
Kim Kyoung-Nam
|
|
|
Abstract
|
|
|
|
Dental implants manufacturers have developed high hydrophilic and rough implant surfaces which in turn exhibited better osseointegration than conventional ones. Based on in vitro studies, sand blast, large grit, acid etching(SLA)-treated surfaces with microstructural characteristics may promote the process of osseointegration. But when the SLA surface is kept dry in the air, it becomes hydrophobic. Appropriate non-thermal atmospheric pressure air plasma jet(air-NTAPPJ) processes render surfaces hydrophilic. The purpose of this research is to air-NTAPPJ on SLA surface treatment to improve the osteogenic functionality. The experiment was carried out through the a cytotoxicity assay and real-time reverse transcriptase-polymerase chain reaction(RT-PCR). The results were that the cell viability and gene expression of ALP, OCN, OPN, and Runx-2 of rMSC enhanced by air-NTAPPJ treated. Thus, air-NTAPPJ application can lead to an improved osseointegration.
|
|
|
KEYWORD
|
|
|
atmospheric pressure plasma, SLA-treated surface, osseointegration
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|